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    Make Room for Bioinformatics

    Posted by: david on Wednesday, September 25, 2002 - 06:41 PM
    Protein News 
    [excerpt] Two tenants are setting up shop this week in the new Fairfax County BioAccelerator, a 15,000-square-foot bioinformatics incubator on the second floor of a modest two-story office building near the Springfield Metro station.


    Smith expects companies in the BioAccelerator will work closely with the new medical campus of Northern Virginia Community College, which is scheduled to open two blocks away in the fall of 2004. "We think there's a great synergy because now we've clustered a couple of facilities in Springfield," he says.



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    metalife knowledgebase

    Posted by: Anonymous on Wednesday, September 11, 2002 - 03:07 PM
    Protein News 
    Dear Gentlemen,

    metalife knowledgebase offers the user a „single entry point“ for research and analysis of available decentralized allocated data. metalife knowledgebase also increasingly integrates data that have been generated by means of own newly developed tools. for instance, by means of the text extraction tools and based on the metalife tmp (tmp = text minding process), data can be derived immediately from scientific publications and used for supplementation of annotations to protein entries or addition of new classes of information to the metalife knowledgebase. the metalife knowledgebase is based on standard components ( pc, sql server 2000). it contains the majority of public accessible molecular biological data as well as indices to the primary data collections, serves as a central in-/output memory for the metalife tools and applications, saves information and knowledge references that are created by highly developed metalife technologies, allows the easy integration of proprietary data and applications, compatible with internet technology. the metalife knowledgebase forms the fundament of our progressive bio-informatics package.

    best regards

    your Metateam

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    METALIFE EXPLORER

    Posted by: Anonymous on Wednesday, September 11, 2002 - 03:07 PM
    Protein News 
    Dear Gentlemen,

    In april 2002 the metalife team released the first version of the metalife explorer.

    with metalife explorer the next central metalife tool is implemented in a first version. It enables the user to access the content of metalife knowledgebase thoroughly. All integrated data sources are exploited with one query. Simple queries as well as advanced queries are possible. The user does not need to know the internal data structures of the different data sources. Cross database queries are possible. A compact yet comprehensive dossier about a gene or a protein can be obtained with a single query. Data obtained from
    structured databases stand in line with text extracted data. Among others, information of the dossiers includes sequences, pathways, publications, patents and relation to diseases. metalife explorer serves as a core part of the metalife working environment.

    best regards

    your Metateam

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    Distributedfolding.org

    Posted by: david on Friday, March 01, 2002 - 02:47 AM
    Protein News 
    Distributedfolding.org is a new project that utilizes its participants' computer's computer processing power to test folding algorithms. Clients are available for Windows, Mac, Linux, and many flavors of Unix.



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    Tools to unravel proteins at forefront of biotech

    Posted by: david on Monday, December 03, 2001 - 07:25 PM
    Protein News 
    [excerpt] DNA microarrays, or biochips, are readily available for sorting tens of thousands of genes simultaneously, but there is still no dominant technology for identifying or characterising proteins, which consist of myriad patterns of 20 amino acids folded into delicate three-dimensional shapes. The shape determines their function.



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    Researchers Rid Cells of 'Mad Cow' Particles

    Posted by: david on Wednesday, August 15, 2001 - 09:11 PM
    Protein News 
    [excerpt] Prions are neither viruses nor bacteria, but infectious agents that cause normally harmless proteins in the body to fold into irregular shapes that cause disease. Prion particles are believed to be responsible for degenerative, deadly brain illnesses including the sheep disease scrapie, bovine spongiform encephalopathy (mad cow disease) in cattle and Creutzfeldt-Jacob disease (CJD) in humans. A version of this illness, variant CJD, is believed to be caused by eating meat from animals infected with mad cow disease.



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    Maggio's Structural Bioinformatics Probes The Power Of Proteins

    Posted by: david on Wednesday, August 01, 2001 - 08:14 PM
    Protein News 
    [excerpt] Structural Bioinformatics doesn't mind sharing its computational techniques because there are enough protein structures to go around, Maggio said. The worldwide pharmaceutical industry is addressing some 150 to 350 targets, but expects within the decade to be presented with 30,000 to 50,000 fully sequenced human genes. Each of those genes would exhibit an average of 150 genetic polymorphisms.


    Scientists say that means the potential universe of protein structures relevant to drug discovery could exceed 5 million.


    Work is still being done to perfect the algorithms Structural Bioinformatics uses to create its three-dimensional models. Still, Maggio suspects Structural Bioinformatics' efforts could be evident in the doctor's office within the next couple years.


    Read the full article.



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    OGS says has faster way to analyse proteins

    Posted by: david on Thursday, July 26, 2001 - 06:44 PM
    Protein News 
    [excerpt] British biotechnology company Oxford GlycoSciences Plc said on Wednesday it had developed a new and faster way to analyse the role of proteins in disease by integrating two advanced technologies.



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    Proteomics: Beyond the Genome

    Posted by: david on Thursday, June 07, 2001 - 07:10 PM
    Protein News 
    [excerpt] In an interview with Amy Tsao, who covers biotechnology for BusinessWeek Online, Gleeson explained the importance of proteomics in the quest to develop better drugs. What follows are are edited excerpts from their conversation:


    Q: Why is proteomics so important?


    A: By understanding what proteins do and how they work together to achieve cellular function, we can get a better picture of how to intervene in disease, which occurs when proteins go wrong.


    Q: How is genomics different from proteomics?


    A: This is a continuum. Genomics doesn't neatly stop at some place and proteomics conveniently begin at another place.... The field of study devoted to identifying genes, discovering genes, and determining gene sequences has been labeled genomics. The field of understanding the functions of those genes, their correlation with a disease, [is] functional genomics.



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    IBM, MDS team up on free biotech research database

    Posted by: david on Wednesday, May 30, 2001 - 07:36 PM
    Protein News 
    [excerpt] International Business Machines Corp. and Canada's MDS Proteomics said on Wednesday they had created a public database of proteomics research aimed at taming the massive amount of data needed to discover how proteins cause disease. The new database was created in conjunction with government agencies from North America and Europe. It will provide researchers with a free, centralized repository of proteomics research, outside the growing number of fee-for-service databases operated by the private sector, such as Celera Genomics Group and Myriad Genetics Inc. -- backed by Hitachi Ltd. and Oracle Corp.




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