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Theoretical Protein Folding
(107 total words in this text)
(684 Reads) 
[Excerpt] The unifying question in this subgroup is: what causes a protein to assume the one unique and biological active structure, rather than the many other possible conformations? A protein is, afterall, just a one-dimensional sequence of amino acids. How is this information translated into a highly specific three-dimensional structure? This question is very important because once we understood why and how a protein achieves this, we could design artificial proteins to perform some desired functions. Topics we are currently working on include: kinetics and thermodynamics of protein folding, protein design, prediction of detailed 3D protein structure via threading, and protein evolution.
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