Theoretical Protein Folding

[Excerpt] The unifying question in this subgroup is: what causes a protein to assume the one unique and biological active structure, rather than the many other possible conformations? A protein is, afterall, just a one-dimensional sequence of amino acids. How is this information translated into a highly specific three-dimensional structure? This question is very important because once we understood why and how a protein achieves this, we could design artificial proteins to perform some desired functions. Topics we are currently working on include: kinetics and thermodynamics of protein folding, protein design, prediction of detailed 3D protein structure via threading, and protein evolution.

---

Read the entire paper here.





This article is from Protein Design
http://www.proteindesign.com/